EPR is making its way to clinical studies It was recently reported by Schaner PE et. all that the Electron Paramagnetic Resonance technique together …
EPR Imaging & Spectroscopy
The new era of preclinical imaging is here!
Discover full potential of EPR Imaging
Electron Resonance Imaging (ERI) allows for measuring materials that contain unpaired electrons and tracking the free radicals. The technique can be applied in many research projects in the areas of oncology research, neurodegeneration, inflammation and many more. Due to the fact that it gives the possibility to receive dynamic measurements and generate whole-body images, it may provide information about many unique microenvironments parameters and represent how they change in time.
Tracking the free radicals mechanisms can help to understand the origins and progressions of various diseases like cancer or neurodegenerative disorder. Redox state, antioxidant capacity or oxidative stress. These biophysical parameters play crucial roles in plenty of physiological mechanisms and pathological dysfunctions.
High-tech solutions for EPR spectroscopy.
We recently designed the L-band spectrometer that is a perfect choice to carry out research on big objects, volumes and in-vivo samples. The spectrometer is equipped with a surface coil resonator that collects good-quality signals from precise localisation. With this device, researchers can study materials containing high water concentrations or perform research on mice, rats or humans(melanoma changes).
The eSPECT+ multiharmonic analyser is an expansion module that can be plugged into the standard X-Band Spectrometer. eSPECT+ increases the sensitivity of the spectrometer’s detection even system even up to 10 times. It is a perfect solution for researchers struggling with weak signals. The expansion module allows for lowering the power level, therefore performing live organisms research. The eSPECT + provides unlimited research possibilities and a new approach to classic EPR spectroscopy measurements.
You may think that the technique can be applied mostly to in-vivo studies, but that is simply just the tip of the iceberg. Due to the fact that the method allows tracking of radicals’ activity and measuring big volumes and lossy samples, it has a huge potential in food or material science research.
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A new therapeutic approach for neurodegenerative diseases. Nowadays, neurodegenerative diseases are a very serious problem. Scientists are trying to discover all the …
EPR is making its way to clinical studies There are subtle physiological differences between normal tissue and tumour tissue. These differences mainly …
Biological differences between cancerous tissues and healthy ones. Nowadays, a fight against cancer seems to be one of the most important issue …
It is possible to conduct in-vivo pO2 measurements in conscious mouse? It is a well-known fact that the oxygenation level is a …
It is possible to obtain 3D map of redox status in a fast and non-invasive way? Antioxidant defence system and stabilized level …
Imaging or Spectroscopy you decide
We know that having all the available options to explore is extremely important to the researchers. We provide solutions to perform both Imaging and Spectroscopy. In the imaging mode, the researcher can generate whole-body images that illustrate the measured microenvironment parameter. To collect the signal with even greater sensitivity the researcher can choose the surface coil resonator to measure the signal locally.