It is possible to conduct in-vivo pO2 measurements in conscious mouse? It is a well-known fact that the oxygenation level is a significant determinant when it comes to identifying and monitoring neoplastic changes. Another fact is that anesthetics affect the physiology of the oxygen inside the animal’s body, which could cause inaccuracies during in vivo …
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Biological differences between cancerous tissues and healthy ones. Nowadays, a fight against cancer seems to be one of the most important issue for scientists. Research groups all around the world are working on new cancer therapies which target tumour cells. One of the approaches to this problem consists in learning the physiological differences between normal …
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EPR is making its way to clinical studies There are subtle physiological differences between normal tissue and tumour tissue. These differences mainly concern characteristics such as redox status and pO2 levels. Thus, imaging methods that enable detection of these biological variations may be valuable in developing treatment strategies. Electron Paramagnetic Resonance Imaging is capable of …
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